Objective: There are a number of different assisted reproduction source, embryo source or even as a carrier of pregnancy. Third party assisted reproduction treatment has been one of the more contentious issues surrounding assisted reproduction, eliciting active debate within many societies with regard to its moral, ethical and religious implications. Oocyte donation may be a treatment option for women having had cancer treatment, women with premature ovarian failure, peri- and post-menopausal women, women who are known carriers of a gene for serious X-linked disorders and autosomal conditions, women with poor oocyte and/or embryo quality or multiple failures during prior attempts to conceive by means of assisted reproduction treatment.Materials and Methods: This descriptive study was carried out in 2007-2008 in five regions (south, north, west, east and center of the city of Shiraz). Two hundred participants (>18 years old) were chosen by cluster Sampling method.Results: A total of 200 respondents constituted the study group, 100 (50%) women and 100 (50%) men. The mean age was 29.40 4.67.62.5% were married, 36.5% were single. 75% women and 71%men did not have any knowledge about oocyte donation.57% had university graduations, 27% had diploma from high school and 15.5% without diploma.25% of women and 57%of men under no circumstances accepted this kind of treatment to do.4% women and 2% men accepted if they had inherited problems in family. 2% women and 2% men accepted if theyhad disabled child. 64% women and 36% men accepted due to women age.Conclusion: The present results indicate that, in general, Iranian people support oocyte donation in some cases as an alternative way of starting a family. Clinics in many countries have difficulties in recruiting altruistically motivated fertile women who would like to donate, and use different strategies for recruitment.